Laizishan anticline southeast carlin-type gold（mineralization） deposit in southwest of Guizhou Province is located in connection between the southwestern margin of Yangzi paralatform and Youjiang orogenic belt，is similar to famous super-large Lannigou gold mine，they are found in the same anticline that is Laizishan anticline，and becomes important exploration area in southwest Guizhou region in recent years.We can point out the prospective areas，favorable positions and confirm target regions and calculate resources by the method of superposition comprehensive geological and geochemistry information in the study.Importantly，based on the geochemistry characteristics of prospecting zone to apply in the method，we get some information：Laizishan anticline of north-east and ramp type thrust fault that distributed in limbs of anticline and parallel anticline，those structures are good for carlin-type gold mineralization；additional，the soil geochemical characteristics contain the level of differentiation of anomalous elements and how to influence gold mineralization；in the aspect of tectonic geochemistry，elementary anomalies of Au，As，Sb，Hg and structural characteristics are combined to determine location of anomalies，relationships elements and gold mineralization；REE and carbon，oxygen isotopes of calcites can compose a discriminant that can show characteristics of fault belts that relate to ore-forming；above all，we can find out that Laizishan anticline southeast carlin-type gold （mineralization） deposit has great potential by the result of calculating resources.