With the development of economy and society，the national environmental protection policy has become increasingly strict.According to the requirements of relevant departments，the mine tailings pond is facing a gradual and comprehensive withdrawal.At present，the utilization and disposal of the tailings dumped in the tailing pond has become a practical problem that has to be solved.Considering the actual situation of the mine studied，the tailings stored in the tailings pond are all fine tailings with small particle size.If used this fine tailings as filling，there are problems such as poor fluidity and low strength of filling body.The chemical composition and particle size of the tailings was determine by X-ray fluorescence spectroscopy and laser particle size analysis.Orthogonal experiments and cement filling experiments were conducted to explore the influence of tailings slurry concentration，cementitious material content，the amount of admixture，and the proportion of fine tailings on the strength and diffusion of the backfill.By using range analysis and variance analysis，the order of importance of the influence of each factor was obtained，and the recommended ratio parameters were determined through multiple regression analysis.Finally，the microstructure of the filling body was further explored through the test results and SEM analysis.The results show that the order of importance of the factors affecting the strength of the filling body is the cementing material content，slurry concentration，admixture content，and the proportion of fine tailings.The order of importance of the factors affecting the diffusion is as follows：The proportion of fine tailings，the amount of additives，the slurry concentration and the amount of cementitious materials.The control variables can obtain the strength growth law of the filling body：Increasing the slurry concentration and the amount of cementitious material can increase the strength of the filling body；Within the appropriate amount，the strength of the filling body increases with the increase of the admixture；The content of tailings will have a more complex impact on the strength of the backfill.According to the regression formula，the recommended ratio parameters for the actual ore house filling are 70% slurry concentration，20% cementitious material content，1‰ admixture content，and 30% fine tailings content.Adding admixtures can make the hydration reaction more fully，thereby increasing its strength.The results show that the strength and fluidity of the fine tailings filling body can meet the requirements of the actual chamber filling.

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